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Randomized Controlled Trial
. 2015 May:42:68-77.
doi: 10.1016/j.cct.2015.03.007. Epub 2015 Mar 24.

The macular degeneration and aging study: Design and research protocol of a randomized trial for a psychosocial intervention with macular degeneration patients

Silvia Sörensen  1 , Katherine White  2 , Wingyun Mak  3 , Katherine Zanibbi  4 , Wan Tang  5 , Amanda O'Hearn  6 , Mark T Hegel  7
Affiliations
Randomized Controlled Trial

The macular degeneration and aging study: Design and research protocol of a randomized trial for a psychosocial intervention with macular degeneration patients

Silvia Sörensen et al. Contemp Clin Trials. 2015 May.

Abstract

Background: Age-related Macular Degeneration (AMD) is the leading cause of irreversible and predictable blindness among older adults with serious physical and mental health consequences. Visual impairment is associated with negative future outlook and depression and has serious consequences for older adults' quality of life and, by way of depression, on long-term survival. Psychosocial interventions have the potential to alleviate and prevent depression symptoms among older AMD patients.

Methods: We describe the protocol of the Macular Degeneration and Aging Study, a randomized clinical trial of a psychosocial Preventive Problem-Solving Intervention. The intervention is aimed at enhancing well-being and future planning among older adults with macular degeneration by increasing preparation for future care.

Results: Adequate randomization and therapeutic fidelity were achieved. Current retention rates were acceptable, given the vulnerability of the population. Acceptability (adherence and satisfaction) was high.

Conclusion: Given the high public health significance and impact on quality of life among older adults with vision loss, this protocol contributes a valid test of a promising intervention for maintaining mental and physical health in this population.

Keywords: Aging; Future planning; Macular degeneration; Preventive problem-solving; Randomized controlled trial.

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Application of PST Steps to PFC Problems
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References

    1. Friedman DS, O’Colmain BJ, Munoz B, et al. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol. 2004;122(4):564–572. - PubMed
    1. Seddon JM, Chen CA. The epidemiology of age-related macular degeneration. Int Ophthalmol Clin. 2004;44(4):17–39. - PubMed
    1. Gottlieb JL. Age-related macular degeneration. JAMA. 2002;288(18):2233–2236. - PubMed
    1. Rovner BW, Casten RJ. Activity loss and depression in age-related macular degeneration. American Journal of Geriatric Psychiatry. 2002;10(3):305–310. - PubMed
    1. Heyl V, Wahl H, Mollenkopf H. Visual capacity, out-of-home activities and emotional well-being in old age: Basic relations and contextual variation. Soc Indicators Res. 2005;74(1):159–189.

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