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. 2015 Apr;44(4 Pt 2):e103-12.
doi: 10.1016/j.lpm.2015.02.009. Epub 2015 Mar 23.

The autoimmune concept of multiple sclerosis

Bryan Nicol  1 , Marion Salou  1 , David-Axel Laplaud  2 , Hartmut Wekerle  3
Affiliations

The autoimmune concept of multiple sclerosis

Bryan Nicol et al. Presse Med. 2015 Apr.

Abstract

Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS). With growing evidence for environmental and genetic factors, MS is now accepted as an autoimmune disease. This complex disease seems to implicate various cell types in both innate and adaptive compartments. Here, we discuss recent advances in the immunological field of MS research.

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