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. 2015 Mar-Apr;32(2):155-7.
doi: 10.4103/0970-2113.152630.

Rare Endobronchial metastasis from uterine leiomyosarcoma

Saswata Ghosh  1 , Susmita Kundu  1 , Amitava Pal  1 , Suman Paul  1
Affiliations

Rare Endobronchial metastasis from uterine leiomyosarcoma

Saswata Ghosh et al. Lung India. 2015 Mar-Apr.

Abstract

Uterine sarcomas are rare and represent approximately 3.2% of all invasive uterine cancers. The annual incidence rate is less than two per 100,000 women. The median age at which uterine sarcoma diagnosed is 56 years. The most common histologic pattern is leiomyosarcoma (LMS) which originates from the myometrium or myometrial vessels. Uterine LMSs are aggressive tumors with high rates of recurrence. The most common mode of spread is hematogenous, with lymphatic spread being rare. Recurrences of up to 70% are reported in stage I and II disease with the site of recurrence being distal, most commonly the lungs or the upper abdomen. But the intra bronchial spread is extremely rare. Here we are reporting a case of uterine LMS with endobronchial metastasis causing whole lung collapse.

Keywords: Endobronchial metastasis; hematogenous; leiomyosarcoma.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Chest X-Ray PA view: Homogenous opacity of the left side with same side mediastinal shifting–probably left whole lung collapse
Figure 2
Figure 2
Contrast-enhanced CT scan of thorax (3-D reconstruction) showing complete collapse of the left lung
Figure 3
Figure 3
Fiber-optic bronchoscopy showing growth protruding from left major bronchus
Figure 4
Figure 4
Histopathology showing tissue partly covered by bronchial epithelium. Subepithelial region showing a tumor composed of spindle-shaped cells arranged in interlacing fascicles. Tumor cells show nuclear pleomorphism and occasional mitotic figures. Tumor cells with bizarre hyperchromatic nuclei are present
See this image and copyright information in PMC

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