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. 2013:2013:906467.
doi: 10.1155/2013/906467. Epub 2013 Apr 4.

Temporal trends in chorioamnionitis by maternal race/ethnicity and gestational age (1995-2010)

Michael J Fassett  1 , Deborah A Wing  2 , Darios Getahun  3
Affiliations

Temporal trends in chorioamnionitis by maternal race/ethnicity and gestational age (1995-2010)

Michael J Fassett et al. Int J Reprod Med. 2013.

Abstract

Objective. To characterize trends in chorioamnionitis (CAM) by maternal race/ethnicity and gestational age. Study Design. We examined trends in CAM from 1995-2010 among singleton births in all Kaiser Permanente Southern California hospitals (n = 471,821). Data were extracted from Perinatal Service System and clinical utilization records. Gestational age- and race/ethnicity-specific biannual diagnosis rates were estimated using the Poisson regression after adjusting for potential confounding factors. Results. Overall diagnosis rates of CAM increased from 2.7% in 1995-1996 to 6.0% in 2009-2010 with a relative increase of 126% (95% confidence intervals [CI] 113%-149%). From 1995-1996 to 2009-2010, CAM increased among the Whites (1.8% to 4.3%, P-value for trend <.001), Blacks (2.2% to 3.7%, P-value for trend <.001), Hispanics (2.4% to 5.8%, P-value for trend <.001), and Asian/Pacific Islanders (3.6% to 9.0%, P-value for trend <.001). The adjusted relative percentage change in CAM from 1995-1996 to 2009-2010 was for Whites [preterm 21% (9%-78%), term 138% (108%-173%)], for Blacks [preterm 24% (-9%-81%), term 62% (30%-101%)], for Hispanics [preterm 31% (3%-66%), term 135% (114%-159%)], and for Asian/Pacific Islanders [preterm 44% (9%-127%), term 145% (109%-188%)]. Conclusion. The findings suggest that CAM diagnosis rate has increased for all race/ethnic groups. This increase is primarily due to increased diagnosis at term gestation.

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Figures

Figure 1
Figure 1
Race/ethnic disparity in rates of chorioamnionitis (CAM). ∗Adjustments were made for maternal age, education, median household income, parity, prenatal care, smoking during pregnancy, and induction of labor.
Figure 2
Figure 2
Temporal trends in the rate of chorioamnionitis (CAM) based on induction of labor subtypes. IOL: induction of labor. ∗Adjustments were made for maternal age, race/ethnicity, education, median household income, parity, prenatal care, and smoking during pregnancy.
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