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Review
. 2015 Jun;166(6):1520-5.e1.
doi: 10.1016/j.jpeds.2015.02.045. Epub 2015 Mar 25.

Re-evaluating "transitional neonatal hypoglycemia": mechanism and implications for management

Affiliations
Review

Re-evaluating "transitional neonatal hypoglycemia": mechanism and implications for management

Charles A Stanley et al. J Pediatr. 2015 Jun.
No abstract available

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure
Figure
Hypoglycemia diagnosis based on plasma metabolic fuel responses. Measurement of major fuels (lactate as a gluconeogenic substrate, FFA from adipose tissue lipolysis, and beta-hydroxybutyrate as the major ketone from hepatic ketogenesis) at a time of hypoglycemia segregates four major groups of disorder: gluconeogenesis defects, ketotic hypoglycemia disorders, fatty acid oxidation defects, and hyperinsulinism or its mimickers. Supplemental tests can be added to support the diagnosis (eg, plasma acyl-carnitine profile, glucagon stimulation test). Abbreviations: FFA (free fatty acids), GH (growth hormone).

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