Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Mar;40(2):161-5.

The prevalence of latent tuberculosis infection and smear positive pulmonary tuberculosis in people with household close contact with tuberculosis in north of iran

Mahmood Moosazadeh  1 , Narges Khanjani  2 , Mohammadreza Parsaee  3
Affiliations

The prevalence of latent tuberculosis infection and smear positive pulmonary tuberculosis in people with household close contact with tuberculosis in north of iran

Mahmood Moosazadeh et al. Iran J Med Sci. 2015 Mar.

Abstract

One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people with close household contact. It was a cross-sectional descriptive, analytical study with the sample size of 668 people from homes with one infected resident. In order to diagnose tuberculosis latent infection, the PPD test was done. To determine patients with smear-positive pulmonary tuberculosis, three sputum samples were taken from every patient and were examined using direct microscopy and culture. Data was analyzed by SPSS20 software. The prevalence of latent tuberculosis infection and smear-positive pulmonary tuberculosis were 42.8% and 0.9% respectively. The prevalence of latent tuberculosis infection and smear-positive pulmonary tuberculosis in people with close household contact were less than that of other studies. However, smear-positive pulmonary tuberculosis in people with close household contact was 199.5 times more than that of the general population.

Keywords: Household close contact; Iran; Prevalence; Tuberculosis.

PubMed Disclaimer

References

    1. Rathi SK, Akhatar MH, Rahbar MH, Azam SI. Prevalence and risk factors associated with tuberculin skin test positivity among household contacts of smear-positive pulmonary tuberculosis cases in Umerkot, Pakistan. Int J Tuberc Lung Dis. 2002;6:851–7. PubMed PMID: 12365570. - PubMed
    1. Madico G, Gilman RH, Checkley W, Cabrera L, Kohlstadt I, Kacena K, et al. Community infection ratio as an indicator for tuberculosis control. Lancet. 1995;345:416–9. doi: 10.1016/S0140-6736(95)90401-8. PubMed PMID: 7853950. - PubMed
    1. Vidal R, Miravitlles M, Caylà JA, Torrella M, Martín N, de Gracia J. A contagiousness study in 3071 familial contacts of tuberculosis patients. Med Clin Barc. 1997;108:361–5. PubMed PMID: 9139141. - PubMed
    1. Morrison J, Pai M, Hopewell PC. Tuberculosis and latent tuberculosis infection in close contacts of people with pulmonary tuberculosis in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis. 2008;8:359–68. doi: 10.1016/S1473-3099(08)70071-9. PubMed PMID: 18450516. - PubMed
    1. Nasehi MM, Moosazadeh M, Amiresmaeili MR, Parsaee MR, Nezammahalleh A. The Epidemiology of Factors Associated with Screening and Treatment Outcomes of Patients with Smear Positive Pulmonary Tuberculosis: A Population-Based Study. J Mazandaran Univ Med Sci. 2012;21:9–18. Persian.

LinkOut - more resources