Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Mar;40(2):185-9.

An intraoral epitheloid hemangioendothelioma masquerading clinically as pyogenic granuloma

Bhargavan Sarojini Sreenivasan  1 , Majo Ambooken  2 , Mayeesh Radhakrishna  1 , Joseph Sebastian  1
Affiliations
Case Reports

An intraoral epitheloid hemangioendothelioma masquerading clinically as pyogenic granuloma

Bhargavan Sarojini Sreenivasan et al. Iran J Med Sci. 2015 Mar.

Abstract

Epitheloid hemangioendothelioma (EHE) is an uncommon angiocentric neoplasm of intermediate malignant potential. This tumor is frequently seen in the lungs and liver, but its presentation in the oral cavity is rare. In the oral cavity, gingival region is the common sites of occurrence. We report a rare case of epitheloid hemangioendothelioma in a 48-year-old male, presenting as a growth in the upper anterior gingiva of five months duration along with a review of its clinicopathological and immunohistochemical characteristics.

Keywords: Epithelioid hemangioendothelioma; Neoplasms; Vascular neoplasm.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Palatal aspect of the swelling between 21 and 22.
Figure 2
Figure 2
Tumor showing spindle and epitheloid cells with intracytoplamic vacuoles indicated by black arrows (×40).
Figure 3
Figure 3
Tumor tissue showing vimentin immuno positivity (×4).
Figure 4
Figure 4
Tumor cells especially the ones forming small vessels and intracytoplamic vacuoles showed strong staining with CD34 (×10).
Figure 5
Figure 5
Tumor cells especially the ones forming small vessels and intracytoplamic vacuoles showed strong staining with CD34 (×40).
See this image and copyright information in PMC

References

    1. Gordón-Núñez MA, Silva eM, Lopes MF, de Oliveira-Neto SF, Maia AP, Galvão HC. Intraoral epithelioid hemangioendothelioma: a case report and review of the literature. Med Oral Patol Oral Cir Bucal. 2010;15:e340–6. PubMed PMID: 20038915. - PubMed
    1. Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer. 1982;50:970–81. doi:10:1002/1097-0142(19820901)50:5%3C970::AID-CNCR2820500527%3E3.0.CO;2-Z. PubMed PMID: 7093931. - PubMed
    1. Bollinger BK, Laskin WB, Knight CB. Epithelioid hemangioendothelioma with multiple site involvement. Literature review and observations. Cancer. 1994;73:610–5. doi:10.1002/1097-0142(19940201)73:3%3C610::AID-CNCR2820730318%3E3.0.CO;2-3. PubMed PMID: 7507796. - PubMed
    1. Manjunatha BS, Kumar GS, Vandana R. Intraoral epithelioid hemangioendothelioma: an intermediate vascular tumor- a case report. Dent Res J. 2009;6:99–102. PubMed PMID: 21528039; PubMed Central PMCID: PMC3075463. - PMC - PubMed
    1. Mohtasham N, Kharrazi AA, Jamshidi S, Jafarzadeh H. Epithelioid hemangioendothelioma of the oral cavity: a case report. J Oral Sci. 2008;50:219–23. doi: 10.2334/josnusd.50.219. PubMed PMID: 18587215. - PubMed

Publication types

LinkOut - more resources