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Case Reports
. 2015 Feb;32(1):56-8.
doi: 10.5114/pdia.2014.40952. Epub 2015 Feb 3.

Lymphoepithelioma-like carcinoma of the skin in a Polish patient

Michał Sobjanek  1 , Magdalena Dobosz  2 , Rafał Pęksa  3 , Małgorzata Sokołowska-Wojdyło  1 , Anna Kowalczyk  4 , Igor Michajłowski  1 , Roman Nowicki  1
Affiliations
Case Reports

Lymphoepithelioma-like carcinoma of the skin in a Polish patient

Michał Sobjanek et al. Postepy Dermatol Alergol. 2015 Feb.

Abstract

Lymphoepithelioma-like carcinoma of the skin (LELCS) is a very rare cutaneous neoplasm with limited metastatic potential. It presents distinctive histopathologic features similar to undifferentiated nasopharyngeal carcinoma and clinical similarities with other skin neoplasms. We present the first case of LELCS in Polish patients. A 72-year-old woman presented with a 12 months' history of painless, solitary tumor on the nose. A wide local excision was performed. There was no evidence of local recurrence 24 months after surgical treatment.

Keywords: lymphoepithelioma-like carcinoma of the skin; surgery.

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Figures

Figure 1
Figure 1
Clinical features of LELCS
Figure 2
Figure 2
Intradermal tumor with expansive borders without epidermal ulceration. The tumor was composed of epithelioid neoplastic cells arranged in a syncytial growth pattern surrounded by a dense lymphocytic infiltrate
Figure 3
Figure 3
Neoplastic epithelioid cells showed an expression of cytokeratins (CK5/6), confirming epithelial differentiation
See this image and copyright information in PMC

References

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