Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015:2015:890802.
doi: 10.1155/2015/890802. Epub 2015 Mar 3.

Drug resistant fetal arrhythmia in obstetric cholestasis

Nahide Altug  1 , Ayse Kirbas  2 , Korkut Daglar  2 , Ebru Biberoglu  2 , Dilek Uygur  2 , Nuri Danisman  2
Affiliations

Drug resistant fetal arrhythmia in obstetric cholestasis

Nahide Altug et al. Case Rep Obstet Gynecol. 2015.

Abstract

Obstetric cholestasis (OC) is a pregnancy specific liver disease characterized by increased levels of bile acid (BA) and pruritus. Raised maternal BA levels could be associated with intrauterine death, fetal distress, and preterm labor and also alter the rate and rhythm of cardiomyocyte contraction and may cause fetal arrhythmic events. We report a case of drug resistant fetal supraventricular tachycardia and concomitant OC. Conclusion. If there are maternal OC and concomitant fetal arrhythmia, possibility of the resistance to antiarrhythmic treatment should be kept in mind.

PubMed Disclaimer

Figures

Figure 1
Figure 1
M-mode imaging is demonstrating a heart rate of 238 bpm.
See this image and copyright information in PMC

References

    1. Villavicencio K. L. Fetal arrhythmias. In: Drose J. A., editor. Fetal Echocardiography. St. Louis, Mo, USA: Elsevier Saunders; 2010. pp. 306–320.
    1. Maeno Y., Hirose A., Kanbe T., Hori D. Fetal arrhythmia: prenatal diagnosis and perinatal management. Journal of Obstetrics and Gynaecology Research. 2009;35(4):623–629. doi: 10.1111/j.1447-0756.2009.01080.x. - DOI - PubMed
    1. Geenes V., Williamson C. Intrahepatic cholestasis of pregnancy. World Journal of Gastroenterology. 2009;15(17):2049–2066. doi: 10.3748/wjg.15.2049. - DOI - PMC - PubMed
    1. Kirbas A., Biberoglu E., Daglar K., et al. Neutrophil-to-lymphocyte ratio as a diagnostic marker of intrahepatic cholestasis of pregnancy. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2014;180:12–15. doi: 10.1016/j.ejogrb.2014.05.042. - DOI - PubMed
    1. Ersoy A. O., Kirbas A., Ozler S., et al. Maternal and fetal serum levels of caspase-cleaved fragments of cytokeratin-18 in intrahepatic cholestasis of pregnancy. The Journal of Maternal-Fetal & Neonatal Medicine. 2015;10:1–5. doi: 10.3109/14767058.2015.1011116. - DOI - PubMed

LinkOut - more resources