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Comment
. 2015 Mar 30;208(7):865.
doi: 10.1083/jcb.2087fta.

Damaged mitochondria get a Parkin ticket

Ben Short
Comment

Damaged mitochondria get a Parkin ticket

Ben Short. J Cell Biol. .

Abstract

In 2008, Narendra et al. revealed that a protein associated with Parkinson’s disease promotes the turnover of dysfunctional mitochondria.

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Figures

None
Parkin (green) is mostly cytosolic in control cells (left) but is recruited to mitochondria (red) in the presence of the uncoupling agent CCCP (right).
See this image and copyright information in PMC

Comment on

References

    1. Narendra, D., et al. . 2008. J. Cell Biol. 183:795–803. - PMC - PubMed
    1. Greene, J.C., et al. . 2003. Proc. Natl. Acad. Sci. USA. 100:4078–4083. - PMC - PubMed
    1. Park, J., et al. . 2006. Nature. 441:1157–1161. - PubMed
    1. Elmore, S.P., et al. . 2001. FASEB J. 15:2286–2287. - PubMed
    1. Narendra, D.P., et al. . 2010. PLoS Biol. 8:e1000298. - PMC - PubMed

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