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. 2015 Aug;135(8):2129-2132.

doi: 10.1038/jid.2015.121. Epub 2015 Mar 31.

Re-Evaluating Cyclosporine A as a Hair Growth-Promoting Agent in Human Scalp Hair Follicles

Nathan J Hawkshaw¹, Iain S Haslam¹, David M Ansell¹, Asim Shamalak², Ralf Paus³

Affiliations

Affiliations

¹ Centre for Dermatology Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.
² Crown Cosma Clinic, Manchester, UK.
³ Centre for Dermatology Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK; Department of Dermatology, University of Muenster, Muenster, Germany. Electronic address: ralf.paus@manchester.ac.uk.

PMID: 25826423
DOI: 10.1038/jid.2015.121

Free article

Re-Evaluating Cyclosporine A as a Hair Growth-Promoting Agent in Human Scalp Hair Follicles

Nathan J Hawkshaw et al. J Invest Dermatol. 2015 Aug.

Free article

. 2015 Aug;135(8):2129-2132.

doi: 10.1038/jid.2015.121. Epub 2015 Mar 31.

Authors

Nathan J Hawkshaw¹, Iain S Haslam¹, David M Ansell¹, Asim Shamalak², Ralf Paus³

Affiliations

¹ Centre for Dermatology Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.
² Crown Cosma Clinic, Manchester, UK.
³ Centre for Dermatology Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, UK; Department of Dermatology, University of Muenster, Muenster, Germany. Electronic address: ralf.paus@manchester.ac.uk.

PMID: 25826423
DOI: 10.1038/jid.2015.121

No abstract available

PubMed Disclaimer

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References

1. Arch Dermatol Res. 1996 Jun;288(7):408-10 - PubMed
1. Lab Invest. 1989 Mar;60(3):365-9 - PubMed
1. Trends Cell Biol. 2011 Feb;21(2):91-103 - PubMed
1. Skin Pharmacol. 1994;7(1-2):101-4 - PubMed
1. J Invest Dermatol. 1993 Mar;100(3):237-9 - PubMed

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