Excessive dynamic airway collapse in a small cohort of chronic obstructive pulmonary disease patients
- PMID: 25829963
- PMCID: PMC4375740
- DOI: 10.4103/1817-1737.150733
Excessive dynamic airway collapse in a small cohort of chronic obstructive pulmonary disease patients
Abstract
Introduction: The prevalence of EDAC (Excessive Dynamic Airway Collapse) has not been studied specifically in patients with chronic obstructive pulmonary disease (COPD).
Objective: The aim of this study was to investigate the prevalence of EDAC in COPD and to determine whether there are clinical factors or functional variables that could influence the degree of expiratory collapse of central airways.
Methods: Prospective observational study of a group of patients with COPD. The degree of tracheobronchial collapse was evaluated by low-dose dynamic airway computed tomography (CT). We recorded clinical and pulmonary function tests data, quality of life and BODE index.
Results: This study included 53 patients with COPD, 46 (87%) males, mean age 65 (SD, 9) years.
Conclusions: The prevalence of EDAC observed in a sample of patients with different levels of COPD severity is low. The degree of dynamic central airway collapse was not related to the patient's epidemiological or clinical features, and did not affect lung function, symptoms, capacity for effort, or quality of life.
Keywords: Chronic pulmonary obstructive disease; central airways; dynamic airway computed tomography; excessive dynamic airway collapse.
Conflict of interest statement
Figures
References
-
- Murgu SD, Colt HG. Tracheobronchomalacia and excessive dynamic airway collapse. Respirol. 2006;11:388–406. - PubMed
-
- Park JG, Edell ES. Dynamic airway collapse: Distinct from tracheomalacia. J Bronchol. 2005;12:143–6. - PubMed
-
- Murgu SD, Colt HG. Treatment of adult tracheobronchomalacia and excessive dynamic airway collapse: An update. Treat Respir Med. 2006;5:103–15. - PubMed
-
- Ernst A, Majid A, Feller-Kopman D, Guerrero J, Boiselle P, Loring SH, et al. Airway stabilization with silicone stents for treating adult tracheobronchomalacia: A prospective observational study. Chest. 2007;132:609–16. - PubMed
-
- Ernst A, Odell DD, Michaud G, Majid A, Herth FF, Gangadharan SP. Central airway stabilization for tracheobronchomalacia improves quality of life in patients with chronic obstructive pulmonary disease. Chest. 2011;140:1162–8. - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources
