Treatment-related acute myeloid leukemia in a chronic lymphocytic leukemia patient: role of fludarabine?

Smith Giri¹, Vijaya Raj Bhatt², Sumesh Khanal³, Apar Kishor Ganti⁴

Affiliations

¹ Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
² Department of Internal Medicine, Division of Hematology-Oncology, University of Nebraska Medical Center, 987680 Nebraska Medical Center, Omaha, NE 68198-7680, USA.
³ Department of Medicine, Institute of Medicine, Tribhuvan University, Nepal.
⁴ Department of Internal Medicine, Veteran's Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, USA.

PMID: 25830016
PMCID: PMC4365054
DOI: 10.1177/2040620714566567

Treatment-related acute myeloid leukemia in a chronic lymphocytic leukemia patient: role of fludarabine?

Smith Giri et al. Ther Adv Hematol. 2015 Apr.

. 2015 Apr;6(2):88-92.

doi: 10.1177/2040620714566567.

Authors

Smith Giri¹, Vijaya Raj Bhatt², Sumesh Khanal³, Apar Kishor Ganti⁴

Affiliations

¹ Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
² Department of Internal Medicine, Division of Hematology-Oncology, University of Nebraska Medical Center, 987680 Nebraska Medical Center, Omaha, NE 68198-7680, USA.
³ Department of Medicine, Institute of Medicine, Tribhuvan University, Nepal.
⁴ Department of Internal Medicine, Veteran's Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, USA.

PMID: 25830016
PMCID: PMC4365054
DOI: 10.1177/2040620714566567

No abstract available

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Conflict of interest statement

Conflict of interest statement: AKG reports serving as a consultant for Boehringer Ingelheim and Otsuka Pharmaceuticals. There are no conflict of interest for any other authors.

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Therapy related AML in a case of chronic lymphocytic leukemia.
Gajendra S, Jha B, Sharma R. Gajendra S, et al. Am J Blood Res. 2023 Apr 15;13(2):77-83. eCollection 2023. Am J Blood Res. 2023. PMID: 37214646 Free PMC article.

References

1. Astrow A. (2003) Fludarabine-related myeloid leukemia. J Clin Oncol 21: 3709–3710. - PubMed
1. Bracey A., Maddox A., Immken L., Hsu S., Marks M. (1989) Coexistence of myelodysplastic syndrome and untreated chronic lymphocytic leukemia with development of acute myeloid leukemia immediately after treatment of chronic lymphocytic leukemia. Am J Hematol 30: 174–180. - PubMed
1. Cheson B., Friedberg J., Kahl B., Van Der Jagt R., Tremmel L. (2010) Bendamustine produces durable responses with an acceptable safety profile in patients with rituximab-refractory indolent non-Hodgkin lymphoma. Clin Lymphoma Myeloma Leuk 10: 452–457. - PubMed
1. Cheson B., Vena D., Barrett J., Freidlin B. (1999) Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias. J Clin Oncol 17: 2454–2460. - PubMed
1. Frederiksen H., Farkas D., Christiansen C., Hasselbalch H., Sorensen H. (2011) Chronic myeloproliferative neoplasms and subsequent cancer risk: a Danish population-based cohort study. Blood 118: 6515–6520. - PubMed

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Treatment-related acute myeloid leukemia in a chronic lymphocytic leukemia patient: role of fludarabine?

Affiliations

Treatment-related acute myeloid leukemia in a chronic lymphocytic leukemia patient: role of fludarabine?

Authors

Affiliations

Conflict of interest statement

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