Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jun;22(3):369-77.
doi: 10.1007/s12028-015-0134-9.

Multi-modality neuro-monitoring: conventional clinical trial design

Alexandros L Georgiadis  1 , Yuko Y Palesch, David Zygun, J Claude Hemphill 3rd, Claudia S Robertson, Peter D Leroux, Jose I Suarez; Second Neurocritical Care Research Conference Investigators
Collaborators, Affiliations
Review

Multi-modality neuro-monitoring: conventional clinical trial design

Alexandros L Georgiadis et al. Neurocrit Care. 2015 Jun.

Abstract

Multi-modal monitoring has become an integral part of neurointensive care. However, our approach is at this time neither standardized nor backed by data from randomized controlled trials. The goal of the second Neurocritical Care Research Conference was to discuss research priorities in multi-modal monitoring, what research tools are available, as well as the latest advances in clinical trial design. This section of the meeting was focused on how such a trial should be designed so as to maximize yield and avoid mistakes of the past.

PubMed Disclaimer

References

    1. N Engl J Med. 2003 Jan 2;348(1):5-14 - PubMed
    1. Stat Med. 1992 Jan 15;11(1):55-66 - PubMed
    1. Crit Care Med. 2007 Jun;35(6):1509-16 - PubMed
    1. Chest. 1991 Dec;100(6):1647-54 - PubMed
    1. J Biopharm Stat. 2006 May;16(3):275-83; discussion 285-91, 293-8, 311-2 - PubMed

Publication types

LinkOut - more resources