doi: 10.1016/0922-4106(89)90016-3.
Estrogen-induced proteins in rat hypothalamus
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- PMID: 2583246
- DOI: 10.1016/0922-4106(89)90016-3
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Estrogen-induced proteins in rat hypothalamus
Eur J Pharmacol.
.
Abstract
The identification of estrogen-inducible genes in specific regions of the central nervous system (CNS) will give information about the mechanisms by which this steroid modulates nervous activity. Two-dimensional gel analysis of the proteins synthesized in vitro from mRNA isolated from control or estrogen-treated rats indicated that the levels of mRNA were increased in the estrogen-treated animals. The levels of mRNA were elevated only in those brain regions that express estrogen receptors.
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