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. 1989 Oct 17;172(4-5):357-62.
doi: 10.1016/0922-4106(89)90016-3.

Estrogen-induced proteins in rat hypothalamus

A Maggi  1 , S Pellegrini, E Bettini
Affiliations

Estrogen-induced proteins in rat hypothalamus

A Maggi et al. Eur J Pharmacol. .

Abstract

The identification of estrogen-inducible genes in specific regions of the central nervous system (CNS) will give information about the mechanisms by which this steroid modulates nervous activity. Two-dimensional gel analysis of the proteins synthesized in vitro from mRNA isolated from control or estrogen-treated rats indicated that the levels of mRNA were increased in the estrogen-treated animals. The levels of mRNA were elevated only in those brain regions that express estrogen receptors.

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