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Case Reports
. 2015;21(2):183-7.
doi: 10.5761/atcs.cr.14-00207. Epub 2015 Mar 31.

Synchronous primary lung cancer presenting with small cell carcinoma and adenocarcinoma

Yoko Yamamoto  1 , Ken Kodama, Hiroyuki Yamato, Masashi Takeda, Hiroyuki Takamori, Takahiro Karasuno
Affiliations
Case Reports

Synchronous primary lung cancer presenting with small cell carcinoma and adenocarcinoma

Yoko Yamamoto et al. Ann Thorac Cardiovasc Surg. 2015.

Abstract

Multiple synchronous primary lung cancers presenting with different histologic types are uncommon. Among reported cases with different histologic findings, only a few had small cell lung cancer (SCLC) and adenocarcinoma. This unusual combination of lung cancers has not been well reported. In this report, we describe two cases of synchronous primary lung cancer presenting with lymph node metastasis of SCLC and early-stage adenocarcinoma. Epidermal growth factor receptor (EGFR) mutation was not detected in either SCLC or adenocarcinoma in the two cases.

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Figures

Fig. 1
Fig. 1
Case 1. Chest computed tomography (CT) showing a part-solid nodule (A) and #12 lymph node swelling (B). Positron emission tomography (PET)-CT showing a part-solid nodule (C) and the #12 lymph node (D). Histologic findings (Hematoxylin-eosin staining) show adenocarcinoma (E) and small cell lung cancer (SCLC) (F).
Fig. 2
Fig. 2
Case 2. Chest computed tomography (CT) showing a ground-glass opacity (A) and #12 lymph node swelling (B). Positron emission tomography (PET)-CT showing a part-solid nodule (C) and the #12 lymph node (D). Histologic findings (Hematoxylin-eosin staining) showing adenocarcinoma (E) and small cell lung cancer (SCLC) (F).
See this image and copyright information in PMC

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