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Review
. 2015 Sep;102(3):383-7.
doi: 10.1007/s12185-015-1792-2. Epub 2015 Apr 2.

Myelodysplastic syndrome with t(9;22)(p24;q11.2), a BCR-JAK2 fusion: case report and review of the literature

Bulent Kantarcioglu  1 , Isik Kaygusuz-Atagunduz, Ant Uzay, Tayfur Toptas, Tulin Firatli Tuglular, Mahmut Bayik
Affiliations
Review

Myelodysplastic syndrome with t(9;22)(p24;q11.2), a BCR-JAK2 fusion: case report and review of the literature

Bulent Kantarcioglu et al. Int J Hematol. 2015 Sep.

Abstract

The human JAK2 gene is mainly targeted by two types of genetic lesions that play roles in the pathogenesis of hematologic malignancies: intragenic mutations and chromosomal translocations. Chromosomal translocations of JAK2 are typically associated with myeloid or lymphoid malignancies with an aggressive course and poor outcome. Here we report a t(9;22)(p24;q11.2) translocation, in a MDS patient and review results associated with BCR-JAK2 fusion reported in the literature.

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References

    1. Br J Haematol. 2008 Aug;142(4):503 - PubMed
    1. Blood. 2012 Aug 16;120(7):1529-31 - PubMed
    1. Leuk Lymphoma. 2011 Sep;52(9):1809-10 - PubMed
    1. Rev Bras Hematol Hemoter. 2013;35(3):218-9 - PubMed
    1. Leuk Lymphoma. 2008 Mar;49(3):388-97 - PubMed

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