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. 2015 Jun;141(6):526-31.
doi: 10.1001/jamaoto.2015.0397.

Sinus balloon catheter dilation in pediatric chronic rhinosinusitis resistant to medical therapy

Affiliations

Sinus balloon catheter dilation in pediatric chronic rhinosinusitis resistant to medical therapy

Fang Wang et al. JAMA Otolaryngol Head Neck Surg. 2015 Jun.

Abstract

Importance: Sinus balloon catheter dilation (SBCD) has been used for chronic rhinosinusitis (CRS). It is necessary to evaluate its effect on children with CRS.

Objective: To evaluate the efficacy of SBCD on pediatric CRS in China.

Design, setting, and participants: A prospective case-control study was conducted from October 1, 2012, to May 31, 2013, in an academic tertiary referral hospital. Participants included a total of 79 patients, aged 7 to 12 years, with CRS resistant to medical therapy.

Interventions: Medical or SBCD treatment of pediatric CRS.

Main outcomes and measures: Age, sex, and results of computed tomographic scan, SBCD (case group) or conservative treatment (control group), sinonasal-5 questionnaire (SN-5), and visual analog scale (VAS) were analyzed and compared.

Results: Data from 79 of 96 patients who had complete follow-up documents were statistically analyzed (42 boys; 37 girls; mean [SD] age, 9.3 [1.7] years). Compared with the preoperative scores, the SN-5 and VAS scores in children with CRS who underwent SBCD with or without adenoidectomy were significantly lower at 3 months (2.5 vs 4.3 for SN-5; P < .001; 3.1 vs 5.2 for VAS; P < .001) and at 1 year (2.9 vs 4.3 for SN-5; P = .001; 3.1 vs 5.2 for VAS; P < .001). Both SN-5 and VAS scores in the control group were significantly decreased at 3 months (3.1 vs 4.2 for SN-5; P = .001; 3.9 vs 5.1 for VAS; P < .001) but not significantly changed at 12 months (3.8 vs 4.2 for SN-5; P = .01; 4.9 vs 5.1 for VAS; P = .54). The SN-5 and VAS scores in the SBCD group were significantly lower than those for controls at 3 months (2.5 vs 3.1 for SN-5; P = .003; 3.1 vs 3.9 for VAS; P = .01) and at 1 year after surgery (2.9 vs 3.8 for SN-5; P < .001; 3.1 vs 4.9 for VAS; P < .001). By the 12-month SN-5 score evaluation, the rates of marked, moderate, and mild improvement were significantly better in the SBCD group (52% [22 of 42], 26% [11 of 42], and 14% [6 of 42], respectively) than in the control group (14% [5 of 37], 19% [7 of 37], and 11% [4 of 37], respectively) (P < .05 for all comparisons).

Conclusions and relevance: The SBCD procedure is a safe and effective technique for pediatric CRS resistant to medical therapy.

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