Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Sep 1;70(1):e28-30.
doi: 10.1097/QAI.0000000000000614.

Transmission Networks of HIV-1 Among Men Who Have Sex With Men in East and Southeast Asia

Kok Keng Tee  1 , Rami Kantor, Somnuek Sungkanuparph, Yutaka Takebe, Patrick Li, Rossana Ditangco, Praphan Phanuphak, Thira Sirisanthana, Benedict Sim, Winai Ratanasuwan, Pacharee Kantipong, Adeeba Kamarulzaman; TREAT Asia Studies to Evaluate Resistance-Monitoring (TASER-M) Database
Collaborators, Affiliations

Transmission Networks of HIV-1 Among Men Who Have Sex With Men in East and Southeast Asia

Kok Keng Tee et al. J Acquir Immune Defic Syndr. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Potential conflicts of interest: The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1. Transmission clusters and phylodynamic profile of HIV-1 subtype B and CRF01_AE among men who have sex with men (MSM) in East and Southeast Asia
(A) Distribution of HIV-1 subtype B and CRF01_AE transmission clusters across seven countries in East and Southeast Asia. Size and frequency of transmission clusters were estimated based on the polymerase gene sequences (HXB2 position: 2252-3263 nt) from 506 and 226 MSM individuals infected with subtype B and CRF01_AE, respectively. In this study, transmission clusters are defined based on statistical supports generated at the internal nodes of the maximum likelihood and Bayesian’s maximum clade credibility (MCC) tree reconstructions (bootstrap values of more than 90% and posterior probability of 1, respectively). (B) Phylodynamic characteristics of HIV-1 subtype B and CRF01_AE transmission clusters. The Bayesian coalescent-based relaxed molecular clock analysis was performed as described elsewhere. The mean time of the most recent common ancestor (tMRCA), displayed in ascending order from the oldest to the youngest cluster, with the 95% highest posterior distribution for each transmission network are shown. The year in which cART was first introduced is also indicated.
See this image and copyright information in PMC

References

    1. Beyrer C, Baral SD, van Griensven F, et al. Global epidemiology of HIV infection in men who have sex with men. Lancet. 2012;380:367–377. - PMC - PubMed
    1. Mayer KH. The next tsunami? HIV spread in Asian men who have sex with men. Clin Infect Dis. 2014;58:1760–1762. - PubMed
    1. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493–505. - PMC - PubMed
    1. Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363:2587–2599. - PMC - PubMed
    1. Hughes GJ, Fearnhill E, Dunn D, Lycett SJ, Rambaut A, Leigh Brown AJ. Molecular phylodynamics of the heterosexual HIV epidemic in the United Kingdom. PLoS Pathog. 2009;5:e1000590. - PMC - PubMed

Publication types

LinkOut - more resources