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Review
. 2015 Apr;62(2):491-508.
doi: 10.1016/j.pcl.2014.11.010.

A practical guide to the diagnosis, treatment, and prevention of neonatal infections

Roberto Parulan Santos  1 , Debra Tristram  2
Affiliations
Review

A practical guide to the diagnosis, treatment, and prevention of neonatal infections

Roberto Parulan Santos et al. Pediatr Clin North Am. 2015 Apr.

Abstract

Neonatal infections continue to cause morbidity and mortality in infants. Among approximately 400,000 infants followed nationally, the incidence rates of early-onset sepsis infection within 3 days of life are 0.98 cases per 1000 live births. Newborn infants are at increased risk for infections because they have relative immunodeficiency. This article provides evidence-based practical approaches to the diagnosis, management, and prevention of neonatal infections.

Keywords: Antibacterial therapy; Antiviral therapy; Early-onset sepsis; Late-onset sepsis; Neonatal antimicrobial stewardship; Neonatal infections; Newborn sepsis; Respiratory viral infections in infants.

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Figures

Fig. 1
Fig. 1
Evaluation of asymptomatic preterm infants (<37-week gestation) with risk factors for sepsis.
Fig. 2
Fig. 2
4 × 6 cm necrotic black eschar on the back of a preterm infant due to Aspergillus fumigatus and the residual scarring after several weeks of combination antifungal agents.
See this image and copyright information in PMC

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