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Review
. 2015 Mar;20(2):83-8.
doi: 10.1093/pch/20.2.83.

Epidemiology and clinical management of tuberculosis in children in Canada

Shaun K Morris  1 , Anne-Marie Demers  2 , Ray Lam  3 , Lisa G Pell  4 , Ryan Jp Giroux  5 , Ian Kitai  6
Affiliations
Review

Epidemiology and clinical management of tuberculosis in children in Canada

Shaun K Morris et al. Paediatr Child Health. 2015 Mar.

Abstract
in English, French

Although often regarded as a foreign disease, latent tuberculosis or tuberculosis disease will be encountered in many clinical situations by the Canadian child health practitioner. There are key differences between tuberculosis in children and adults. In the present article, the changing epidemiology of tuberculosis in children in Canada and around the world, the pathogenesis of infection, diagnostic tests, and clinical management of childhood latent tuberculosis and tuberculosis disease are reviewed.

Même si la tuberculose latente et la tuberculose sont souvent considérées comme des maladies étrangères, le dispensateur canadien de soins des enfants les observera souvent dans bien des situations cliniques. Il y a des différences clés entre la tuberculose chez l’enfant et chez l’adulte. Dans le présent article, les auteurs analysent l’évolution de l’épidémiologie de la tuberculose chez les enfants du Canada et de l’étranger, la pathogenèse de l’infection, les tests diagnostiques et la prise en charge de la tuberculose latente et de la tuberculose pendant l’enfance.

Keywords: Children; Diagnosis; Mycobacterium tuberculosis; Pathogenesis; Treatment; Tuberculosis.

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Figures

Figure 1)
Figure 1)
How to manage a child exposed to infectious tuberculosis. IGRA Interferon-gamma release assay; LTBI Latent tuberculosis infection; TST Tuberculin skin test
See this image and copyright information in PMC

References

    1. Public Health Agency of Canada and Canadian Thoracic Society Canadian TB Standards, 7th Edition. Can Respir J. 2013;20(Suppl A)
    1. World Health Organization Tuberculosis. 2014. Fact Sheet 104.
    1. Dodd PJ, Gardiner E, Coghlan R, Seddon JA. Burden of childhood tuberculosis in 22 high-burden countries: A mathematical modelling study. Lancet Glob Heal. 2014;2:e453–9. - PubMed
    1. Clark M, Hui C. Children from Baffin Island have a disproportionate burden of tuberculosis in Canada: Data from the Children’s Hospital of Eastern Ontario (1998–2008) BMC Pediatr. 2010;10:102. - PMC - PubMed
    1. Centre for Communicable Diseases and Infection Control. Public Health Agency of Canada Tuberculosis in Canada 2012 – Pre-Release Introduction. 2014. < www.phac-aspc.gc.ca/tbpc-latb/pubs/tbcan12pre/index-eng.php> (Accessed December 15, 2014).

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