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Review
. 2015 Jan-Mar;4(1):41-4.
doi: 10.4103/2278-330X.149951.

Giant solitary trichoepithelioma

Bhavuray Teli  1 , P B Thrishuli  2 , R Santhosh  1 , D N Amar  3 , Shravan Rajpurohit  1
Affiliations
Review

Giant solitary trichoepithelioma

Bhavuray Teli et al. South Asian J Cancer. 2015 Jan-Mar.

Abstract

Adnexal tumors like giant solitary trichoepitheliomas are uncommon to most of us to permit a ready familiarity with them. Information regarding the genesis, clinical profile, behavior, and management options for this tumor is limited. There are 18 cases reported in the world literature till date. This review attempts to provide insight to this rare tumor. Our search included indexed literature from Pubmed, Directory of Open Access Journals, Health Inter Network Access to Research Initiative and Google databases in addition to standard dermatology texts. Giant solitary trichoepithelioma is a rare trichogenic tumor with potential for local recurrence. It has predilection for the older age, but may present at any age including at birth. It has close resemblance to basal cell carcinoma and other skin adnexal tumors - clinically, cytologically, and histologically. CD10, CD 34, PHLDA1 but not p75NTR are useful adjunct markers. Surgical excision is the standard treatment. Recurrence and possible transformation into BCC cautions follow up at regular intervals.

Keywords: Brooke-Spiegel syndrome; Rombo syndrome; giant solitary trichoepithelioma; trichogenic tumor.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Pedunculated 6 × 4 cm GST with lobular surface in right mammary area with broad base of 1.5 cm
See this image and copyright information in PMC

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