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Comment

. 2015 Apr;21(4):308-10.

doi: 10.1038/nm.3834.

Harnessing gene repression to inhibit leukemia

Peter J Harte¹, Patricia Ernst²

Affiliations

Affiliations

¹ Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
² Departments of Pediatrics and Pharmacology, University of Colorado, Denver/Anschutz Medical Campus, Aurora, Colorado, USA.

PMID: 25849269
DOI: 10.1038/nm.3834

Comment

Harnessing gene repression to inhibit leukemia

Peter J Harte et al. Nat Med. 2015 Apr.

. 2015 Apr;21(4):308-10.

doi: 10.1038/nm.3834.

Authors

Peter J Harte¹, Patricia Ernst²

Affiliations

¹ Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
² Departments of Pediatrics and Pharmacology, University of Colorado, Denver/Anschutz Medical Campus, Aurora, Colorado, USA.

PMID: 25849269
DOI: 10.1038/nm.3834

No abstract available

PubMed Disclaimer

Comment on

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
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References

1. Annu Rev Biochem. 2004;73:417-35 - PubMed
1. Blood. 2013 Aug 8;122(6):1017-25 - PubMed
1. Cell Rep. 2014 May 22;7(4):1239-47 - PubMed
1. Genes Cancer. 2013 Mar;4(3-4):148-63 - PubMed
1. Exp Hematol. 2014 Dec;42(12):995-1012 - PubMed

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