Opportunities for drug repositioning from phenome-wide association studies

Affiliations

¹ 1] Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA. [2] Biomedical Statistics and Bioinformatics, Mayo Clinic, Rochester, Minnesota, USA and Nationwide Children's Hospital, Columbus, Ohio, USA.
² Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA.
³ School of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA.
⁴ Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA.

Comment

Majid Rastegar-Mojarad et al. Nat Biotechnol. 2015 Apr.

. 2015 Apr;33(4):342-5.

doi: 10.1038/nbt.3183.

¹ 1] Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA. [2] Biomedical Statistics and Bioinformatics, Mayo Clinic, Rochester, Minnesota, USA and Nationwide Children's Hospital, Columbus, Ohio, USA.
² Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA.
³ School of Pharmacy, University of Wisconsin, Madison, Wisconsin, USA.
⁴ Center for Human Genetics, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, USA.

No abstract available

Comment on

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.
Denny JC, Bastarache L, Ritchie MD, Carroll RJ, Zink R, Mosley JD, Field JR, Pulley JM, Ramirez AH, Bowton E, Basford MA, Carrell DS, Peissig PL, Kho AN, Pacheco JA, Rasmussen LV, Crosslin DR, Crane PK, Pathak J, Bielinski SJ, Pendergrass SA, Xu H, Hindorff LA, Li R, Manolio TA, Chute CG, Chisholm RL, Larson EB, Jarvik GP, Brilliant MH, McCarty CA, Kullo IJ, Haines JL, Crawford DC, Masys DR, Roden DM. Denny JC, et al. Nat Biotechnol. 2013 Dec;31(12):1102-10. doi: 10.1038/nbt.2749. Nat Biotechnol. 2013. PMID: 24270849 Free PMC article.