Criteria for biological reproducibility: what does "n" mean?

Kristen Naegle¹, Nancy R Gough², Michael B Yaffe³

Affiliations

¹ Biomedical Engineering and the Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA. myaffe@mit.edu knaegle@wustl.edu.
² Chief Scientific Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
³ David H. Koch Institute for Integrative Cancer Research, The Broad Institute, and the Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA. myaffe@mit.edu knaegle@wustl.edu.

PMID: 25852186
DOI: 10.1126/scisignal.aab1125

Review

Criteria for biological reproducibility: what does "n" mean?

Kristen Naegle et al. Sci Signal. 2015.

. 2015 Apr 7;8(371):fs7.

doi: 10.1126/scisignal.aab1125.

Authors

Kristen Naegle¹, Nancy R Gough², Michael B Yaffe³

Affiliations

¹ Biomedical Engineering and the Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, MO 63130, USA. myaffe@mit.edu knaegle@wustl.edu.
² Chief Scientific Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
³ David H. Koch Institute for Integrative Cancer Research, The Broad Institute, and the Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA. myaffe@mit.edu knaegle@wustl.edu.

PMID: 25852186
DOI: 10.1126/scisignal.aab1125

Abstract

This Focus tackles the issue of technical versus biological replicates, what constitutes appropriate biological replicates, and appropriate statistical analysis for data with small sample sizes.

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Criteria for biological reproducibility: what does "n" mean?

Affiliations

Criteria for biological reproducibility: what does "n" mean?

Authors

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources