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. 2015 Apr 7;21(13):3888-92.
doi: 10.3748/wjg.v21.i13.3888.

Esophageal variceal pressure influence on the effect of ligation

Zhi-Qun Li  1 , En-Qiang LingHu  1 , Min Hu  1 , Wei-Min Li  1 , Qi-Yang Huang  1 , Yong-Wei Zhao  1
Affiliations

Esophageal variceal pressure influence on the effect of ligation

Zhi-Qun Li et al. World J Gastroenterol. .

Abstract

Aim: To explore the effect of in vitro porcine esophageal variceal pressure on complete ligation degree for polycyclic ligators.

Methods: An in vitro model of experimental porcine venous vessels was used to test various venous pressures. Three treatment groups were designated according to the preset pressure range: P1 = 25-30 cmH₂O; P₂ = 35-40 cmH₂O; P₃ = 45-50 cmH2O. The effect of pressure on ligation was assessed and compared among the groups.

Results: Complete ligation was achieved at a rate of 56.25% (18/32) in group P1, 37.5% (12/32) in group P₂, and 33.33% (11/33) in group P₃ (χ (2) = 3.6126; P = 0.0573).

Conclusion: Higher variceal pressures impair the ligation completion rate. Therefore, measuring variceal pressure may help predict the effect of endoscopic ligation and guide treatment choice.

Keywords: Endoscopic variceal ligation; Mold of animal; Variceal pressure.

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Figures

Figure 1
Figure 1
Measuring venous pressure.
Figure 2
Figure 2
Established submucosal tunnel.
Figure 3
Figure 3
In vitro ligation model of pig esophageal varices and judgment of the effect. A: Ligation model; B: Complete ligation (100%); C: Partial ligation (≤ 50%); D: No ligation (0%).
See this image and copyright information in PMC

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