The foundation of precision medicine: integration of electronic health records with genomics through basic, clinical, and translational research

Affiliations

¹ Biochemistry and Molecular Biology, Center for Systems Genomics, The Pennsylvania State University University Park, PA, USA ; Institute of Biomedical and Translational Informatics, Geisinger Health System Danville, PA, USA.
² Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic Rochester, MN, USA.
³ The Sigfried and Janet Weis Center for Research, Geisinger Health System Danville, PA, USA ; Department of Surgery, Temple University School of Medicine Philadelphia, PA, USA.

Marylyn D Ritchie et al. Front Genet. 2015.

. 2015 Mar 17:6:104.

doi: 10.3389/fgene.2015.00104. eCollection 2015.

¹ Biochemistry and Molecular Biology, Center for Systems Genomics, The Pennsylvania State University University Park, PA, USA ; Institute of Biomedical and Translational Informatics, Geisinger Health System Danville, PA, USA.
² Division of Biomedical Statistics and Informatics, Department of Health Science Research, Mayo Clinic Rochester, MN, USA.
³ The Sigfried and Janet Weis Center for Research, Geisinger Health System Danville, PA, USA ; Department of Surgery, Temple University School of Medicine Philadelphia, PA, USA.

No abstract available

Keywords: EHR; electronic health records; genomic medicine; genomics; precision medicine.

References

1. Almoguera B., Vazquez L., Connolly J. J., Bradfield J., Sleiman P., Keating B., et al. (2014). Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes. Front. Genet. 5:96. 10.3389/fgene.2014.00096 - DOI - PMC - PubMed
1. Connolly J. J., Glessner J. T., Almoguera B., Crosslin D. R., Jarvik G. P., Sleiman P. M., et al. (2014). Copy number variation analysis in the context of electronic medical records and large-scale genomics consortium efforts. Front. Genet. 5:51. 10.3389/fgene.2014.00051 - DOI - PMC - PubMed
1. Crawford D. C., Crosslin D. R., Tromp G., Kullo I. J., Kuivaniemi H., Hayes M. G., et al. (2014). eMERGEing progress in genomics—the first seven years. Front. Genet. 5:184. 10.3389/fgene.2014.00184 - DOI - PMC - PubMed
1. Cronin R. M., Field J. R., Bradford Y., Shaffer C. M., Carroll R. J., Mosley J. D., et al. (2014). Phenome Wide Association Studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index. Front. Genet. 5:250. 10.3389/fgene.2014.00250 - DOI - PMC - PubMed
1. Crosslin D. R., Tromp G., Burt A., Kim D. S., Verma S. S., Lucas A. M., et al. (2014). Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to Electronic Health Records. Front. Genet. 5:352. 10.3389/fgene.2014.00352 - DOI - PMC - PubMed