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Review
. 2015 Feb;73(1):1-9.
doi: 10.1093/femspd/ftu015. Epub 2014 Dec 4.

Infection with Chlamydia pneumoniae as a cause of coronary heart disease: the hypothesis is still untested

J Thomas Grayston  1 , Robert J Belland  2 , Gerald I Byrne  2 , Cho Chou Kuo  3 , Julius Schachter  4 , Walter E Stamm  5 , Guangming Zhong  6
Affiliations
Review

Infection with Chlamydia pneumoniae as a cause of coronary heart disease: the hypothesis is still untested

J Thomas Grayston et al. Pathog Dis. 2015 Feb.

Abstract

Review of the possible role of Chlamydia pneumoniae infection in the pathogenesis of heart disease.

Keywords: antibiotic; clinical trials; treatment.

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Figures

None
Review of the possible role of Chlamydia pneumoniae infection in the pathogenesis of heart disease.
Figure 1.
Figure 1.
Prevalence of C. pneumoniae MIF IgG antibody by age in Seattle children (Grayston 1994).
Figure 2.
Figure 2.
Prevalence of MIF antibody to C. pneumoniae (TWAR) by age in among 5242 persons in Seattle. IgG titers ranged from 8 to 256 (Grayston 1992).
See this image and copyright information in PMC

References

    1. Al-Marzooq F, Imad MA, How SH, et al. Development of multiplex real-time PCR for the rapid detection of five bacterial causes of community acquired pneumonia. Trop Biomed. 2011;28:545–56. - PubMed
    1. Aldous MB, Grayston JT, Wang SP, et al. Seroepidemiology of Chlamydia pneumoniae TWAR infection in Seattle families, 1966–1979. J Infect Dis. 1992;166:646–9. - PubMed
    1. Alpert BS, Collins RT. Assessment of vascular function: pulse wave velocity. J Pediatr. 2007;150:219–20. - PubMed
    1. Andraws R, Berger JS, Brown DL. Effects of antibiotic therapy on outcomes of patients with coronary artery disease: a meta-analysis of randomized controlled trials. JAMA. 2005;293:2641–7. - PubMed
    1. Aoyama T, Chen M, Fujiwara H, et al. LOX-1 mediates lysophosphatidylcholine-induced oxidized LDL uptake in smooth muscle cells. FEBS Lett. 2000;467:217–20. - PubMed

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