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Comment
. 2015 Apr 8;17(4):419-20.
doi: 10.1016/j.chom.2015.03.010.

Host autophagy combating S. aureus: α-toxin will be tolerated

Michael E Powers  1 , Juliane Bubeck Wardenburg  2
Affiliations
Comment

Host autophagy combating S. aureus: α-toxin will be tolerated

Michael E Powers et al. Cell Host Microbe. .

Abstract

Autophagy regulates the degradation of both cellular components and invading intracellular pathogens. In this issue of Cell Host & Microbe, Maurer et al. (2015) reveal that cellular autophagy decreases host sensitivity to Staphylococcus aureus α-toxin via reduced expression of the toxin receptor ADAM10, thus rendering the host tolerant to disease.

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References

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