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. 2015 Jan;141(1):46-54.
doi: 10.4103/0971-5916.154494.

Health & nutritional status of HIV infected children in Hyderabad, India

G Krishna Swetha, R Hemalatha  1 , U V Prasad, Vasudev Murali, K Damayanti, V Bhaskar
Affiliations

Health & nutritional status of HIV infected children in Hyderabad, India

G Krishna Swetha et al. Indian J Med Res. 2015 Jan.

Abstract

Background & objectives: Information on nutritional status of HIV infected children from India is lacking and is required before taking up nutritional supplementation trials. Thus, the aim of the present study was to assess the growth and morbidity status of HIV infected children over a period of one year in a city in southern India.

Methods: This was an observational study carried out between July 2009 and February 2011, at two orphanages in Hyderabad, India. Seventy seven HIV-positive children aged between 1 and half and 15 years, both on and not on antiretroviral therapy (ART) were included. Nutritional status was assessed longitudinally for one year by weight gain, linear growth and body composition. Serum samples were analyzed for haemoglobin, micronutrients, CD4 and CD8 counts. Dietary intakes were assessed by institutional diet survey and morbidity data were recorded every day for 12 months.

Results: Mean energy intakes were less than recommended dietary allowance (RDA) in all age groups. Iron and folate intakes were less than 50 per cent of RDA; 46 (59.7%) children were stunted, 36 (46.8%) were underweight and 15 (19.5%) had low BMI for age. Anaemia was observed in 35 (45.5%) children. Micronutrient deficiencies such as vitamin D (40/77; 51.9%), vitamin A (11/77; 14.3%), folate (37/77; 48.1%), iron (38/77; 49.3%) were widely prevalent. HIV viral load was higher in children not on ART and those with morbidity. Respiratory (36.6%) and dermatological illnesses (18.8%) were the commonest presentations.

Interpretation & conclusions: Acute, chronic malnutrition and micronutrient deficiencies were common in HIV infected children, especially in those not on ART and having morbidity. With severe malnutrition being an alarming consequence of HIV, prophylactic nutritive care should be considered for integration into HIV care strategies besides initiation of ART to improve the nutritional status and quality of life of these children.

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Figures

Fig.
Fig.
Dietary intakes of HIV infected children in comparison with recommended dietary allowance (RDA).
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References

    1. New Delhi: National Institute of Medial Statistics (ICMR), NACO, DAC, Ministry of Health & Family Welfare; 2012. National AIDS Control Organization. Technical report: India HIV estimates.
    1. Fontana M, Zuin G, Plebani A, Bastoni K, Visconti G, Principi N. Body composition in HIV-infected children: relations with disease progression and survival. Am J Clin Nutr. 1999;69:1282–6. - PubMed
    1. Beisel WR. Nutrition and immune function: Overview. J Nutr. 1996;126:2611S–5S. - PubMed
    1. Report on the global AIDS epidemic 2008. [accessed on May 4, 2009]. Available from: http://www.unaids.org/en/KnowledgeCentre/HIV data/globalReport/2008/2008... .
    1. Gillespie S, Greener R, Whiteside A, Whitworth J. Investigating the empirical evidence for understanding vulnerability and the associations between poverty, HIV infection and AIDS impact. AIDS. 2007;21(Suppl. 7):S1–4. - PubMed