The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT
- PMID: 25858058
- DOI: 10.1161/CIRCRESAHA.115.306298
The direct actions of flecainide on the human cardiac ryanodine receptor: keeping open the debate on the mechanism of action of local anesthetics in CPVT
Keywords: Editorials; flecainide; heart; polymorphic catecholergic ventricular tachycardia; ryanodine receptor calcium release channel; sarcoplasmic reticulum.
Comment on
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The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2.Circ Res. 2015 Apr 10;116(8):1324-35. doi: 10.1161/CIRCRESAHA.116.305347. Epub 2015 Feb 3. Circ Res. 2015. PMID: 25648700
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