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. 2015 Apr;71(2):197-200.
doi: 10.1016/j.mjafi.2012.09.004. Epub 2012 Nov 29.

Histiocytosis

Affiliations

Histiocytosis

D Vashisht et al. Med J Armed Forces India. 2015 Apr.
No abstract available

Keywords: Langerhans cell histiocytosis; Parotidomegaly; Seborrhoeic dermatitis.

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Figures

Fig. 1
Fig. 1
Diffuse erythematous plaques and papules with crusting involving face and scalp.
Fig. 2
Fig. 2
Multiple, discrete, scaly, red-brown, papules over chest and onychomadesis.
Fig. 3
Fig. 3
(A) H&E stained section (×400) of skin showing with reniform nuclei (short arrow) and mixed inflammatory infiltrate including eosinophils (long arrow). (B) IHC staining for CD1a (×100) showing diffuse positivity in histiocytes in the dermis.
Fig. 4
Fig. 4
Axial & coronal CT sections show variable sized, bizarre thin walled cysts in upper zones & large cystic changes involving the costophrenic angles.
Fig. 5
Fig. 5
Axial & coronal T2W MRI images show large cystic changes in the parotid & submandibular glands bilaterally.

References

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    1. Langerhans P. Über die Nerven der menschlichen Haut. Arch Abl B Pathol. 1868;44:325–337.
    1. Chu T. Langerhans cell histiocytosis. Australas J Dermatol. 2001 Nov;42(4):237–242. - PubMed
    1. Histiocytosis syndromes in children Writing group of the histiocyte society. Lancet. 1987 Jan 24;1(8526):208–209. - PubMed
    1. Kusumkumary P., Kumari P.T., Chellam V.G., James F.V., Nair K.M. Langerhans cell histiocytosis in children less than 2 years of age. Indian Pediatr. 1999;36:29–36. - PubMed

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