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Case Reports
. 2015 Feb;7(2):50-2.

Brown tumor of mandible in association with primary hyperparathyroidism: a case report

Akshay Dinakar Shetty  1 , J Namitha  2 , Leena James  3
Affiliations
Case Reports

Brown tumor of mandible in association with primary hyperparathyroidism: a case report

Akshay Dinakar Shetty et al. J Int Oral Health. 2015 Feb.

Abstract

Brown tumors are giant cell focal lesion that arises as a result of abnormal bone metabolism in patients with hyperparathyroidism (HPT). The lesions localize in areas of extensive bone resorption, which is replaced by fibrovascular tissue and giant cells with abundant deposits hemorrhage and hemosiderin. A rare case of brown tumor of mandible in a 22-year-old woman is reported here. This case emphasizes the importance of a detailed systemic investigation for all lesions in the maxillofacial region and also discusses the diverse presentations associated with primary HPT.

Keywords: Brown tumor; giant cell lesion; mandible; primary hyperparathyroidism.

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Conflict of interest statement

Conflicts of Interest: None

Figures

Figure 1
Figure 1
A diffuse swelling was on left side of the face.
Figure 2
Figure 2
An ulceroproliferative growth in the vestibule on left side, extending from the mesial aspect of lower left canine to the retromolar region.
Figure 3
Figure 3
Orthopantamogram with large unilocular radiolucency on left side, extending from mandibular first premolar to mandibular third molar.
Figure 4
Figure 4
Parathyroid technetium scintiscan showing abnormally high uptake observed at the lower pole of the right thyroid lobe.
See this image and copyright information in PMC

References

    1. Movahedian B, Razavi SM, Hasheminia D, Rezaei M. Simultaneous maxillary and mandibular brown tumors in secondary hyperparathyroidism: A case report. Dent Res J. 2008;5(1):41–5.
    1. Selvi F, Cakarer S, Tanakol R, Guler SD, Keskin C. Brown tumour of the maxilla and mandible: A rare complication of tertiary hyperparathyroidism. Dentomaxillofac Radiol. 2009;38(1):53–8. - PubMed
    1. Jebasingh F, Jacob JJ, Shah A, Paul TV, Seshadri MS. Bilateral maxillary brown tumours as the first presentation of primary hyperparathyroidism. Oral Maxillofac Surg. 2008;12(2):97–100. - PubMed
    1. Soundarya N, Sharada P, Prakash N, Pradeep G. Bilateral maxillary brown tumors in a patient with primary hyperparathyroidism: Report of a rare entity and review of literature. J Oral Maxillofac Pathol. 2011;15:56–9. - PMC - PubMed
    1. Suarez-Cunqueiro MM, Schoen R, Kersten A, Klisch J, Schmelzeisen R. Brown tumor of the mandible as first manifestation of atypical parathyroid adenoma. J Oral Maxillofac Surg. 2004;62(8):1024–8. - PubMed

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