A collective path toward regeneration

Théo Maire¹, Hyun Youk²

Affiliations

¹ Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands.
² Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands. Electronic address: h.youk@tudelft.nl.

PMID: 25860601
DOI: 10.1016/j.cell.2015.03.039

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A collective path toward regeneration

Théo Maire et al. Cell. 2015.

Free article

. 2015 Apr 9;161(2):195-6.

doi: 10.1016/j.cell.2015.03.039.

Authors

Théo Maire¹, Hyun Youk²

Affiliations

¹ Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands.
² Department of Bionanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands; Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, the Netherlands. Electronic address: h.youk@tudelft.nl.

PMID: 25860601
DOI: 10.1016/j.cell.2015.03.039

Abstract

How do cells collectively control an organ's behavior? By plucking various numbers of hairs from the mouse skin, Chen et al. show that hairs regenerate only when a sufficiently high density of them are plucked. Remarkably, a hair follicle can only regenerate in concert with other follicles, but not autonomously.

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Organ-level quorum sensing directs regeneration in hair stem cell populations.
Chen CC, Wang L, Plikus MV, Jiang TX, Murray PJ, Ramos R, Guerrero-Juarez CF, Hughes MW, Lee OK, Shi S, Widelitz RB, Lander AD, Chuong CM. Chen CC, et al. Cell. 2015 Apr 9;161(2):277-90. doi: 10.1016/j.cell.2015.02.016. Cell. 2015. PMID: 25860610 Free PMC article.

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A collective path toward regeneration

Affiliations

A collective path toward regeneration

Authors

Affiliations

Abstract

Comment on

Publication types

MeSH terms

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Full Text Sources

Medical