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. 2015 Apr 9;161(2):418-418.e1.
doi: 10.1016/j.cell.2015.03.043.

SnapShot: Origins of DNA replication

Rachel L Creager  1 , Yulong Li  1 , David M MacAlpine  1
Affiliations
Free article

SnapShot: Origins of DNA replication

Rachel L Creager et al. Cell. .
Free article

Abstract

The fundamental unit of DNA replication, the replicon, is governed by a cis-acting replicator sequence and a trans-activating initiator factor. Despite the increased size and complexity of eukaryotic genomes, eukaryotic DNA replication continues to be guided by the fundamental principles and concepts established in the replicon model.

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