Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Apr;78(2):64-71.
doi: 10.4046/trd.2015.78.2.64. Epub 2015 Apr 2.

Diagnosis of pulmonary tuberculosis: recent advances and diagnostic algorithms

Yon Ju Ryu  1
Affiliations
Review

Diagnosis of pulmonary tuberculosis: recent advances and diagnostic algorithms

Yon Ju Ryu. Tuberc Respir Dis (Seoul). 2015 Apr.

Abstract

Pulmonary tuberculosis (TB) persists as a great public health problem in Korea. Increases in the overall age of the population and the rise of drug-resistant TB have reinforced the need for rapid diagnostic improvements and new modalities to detect TB and drug-resistant TB, as well as to improve TB control. Standard guidelines and recent advances for diagnosing pulmonary TB are summarized in this article. An early and accurate diagnosis of pulmonary TB should be established using chest X-ray, sputum microscopy, culture in both liquid and solid media, and nucleic acid amplification. Chest computed tomography, histopathological examination of biopsy samples, and new molecular diagnostic tests can be used for earlier and improved diagnoses, especially in patients with smear-negative pulmonary TB or clinically-diagnosed TB and drug-resistant TB.

Keywords: Diagnosis; Lung; Tuberculosis.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: No potential conflict of interest relevant to this article was reported.

References

    1. World Health Organization. Global tuberculosis report 2014 [Internet] Geneva: World Health Organization; 2014. [cited 2015 Mar 1]. Available from: http://apps.who.int/iris/bitstream/10665/137094/1/9789241564809_eng.pdf?....
    1. Park YK, Park YS, Na KI, Cho EH, Shin SS, Kim HJ. Increased tuberculosis burden due to demographic transition in Korea from 2001 to 2010. Tuberc Respir Dis. 2013;74:104–110. - PMC - PubMed
    1. World Health Organization. Early detection of tuberculosis: an overview of approaches, guidelines and tools [Internet] Geneva: World Health Organization; 2011. [cited 2015 Mar 1]. Available from: http://www.who.int/iris/handle/10665/70824#sthash.TN5snAtB.dpuf.
    1. Woodring JH, Vandiviere HM, Fried AM, Dillon ML, Williams TD, Melvin IG. Update: the radiographic features of pulmonary tuberculosis. AJR Am J Roentgenol. 1986;146:497–506. - PubMed
    1. Krysl J, Korzeniewska-Kosela M, Muller NL, FitzGerald JM. Radiologic features of pulmonary tuberculosis: an assessment of 188 cases. Can Assoc Radiol J. 1994;45:101–107. - PubMed