One small step for muscle: a new micropeptide regulates performance
- PMID: 25863244
- DOI: 10.1016/j.cmet.2015.03.013
One small step for muscle: a new micropeptide regulates performance
Abstract
Micropeptides represent an emerging class of eukaryotic regulators that are easily missed in conventional genome annotation. Anderson et al. (2015) describe how a new tissue-specific micropeptide, myoregulin (MLN), interacts with the skeletal muscle calcium handling machinery to moderate contractile activity, representing a promising drug target for improving muscle performance.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.Cell. 2015 Feb 12;160(4):595-606. doi: 10.1016/j.cell.2015.01.009. Epub 2015 Jan 29. Cell. 2015. PMID: 25640239 Free PMC article.
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