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. 2015 Mar;24(2):94-97.
doi: 10.1111/ajad.12160.

Typologies of positive psychotic symptoms in methamphetamine dependence

Chad A Bousman  1   2   3   4 , Rebecca McKetin  5 , Richard Burns  5 , Steven Paul Woods  6 , Erin E Morgan  6 , J Hampton Atkinson  6   7 , Ian P Everall  1   4   8 , Igor Grant  6 ; Translational Methamphetamine AIDS Research Center (TMARC) Group
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Typologies of positive psychotic symptoms in methamphetamine dependence

Chad A Bousman et al. Am J Addict. 2015 Mar.

Abstract

Background and objectives: Understanding methamphetamine associated psychotic (MAP) symptom typologies could aid in identifying individuals at risk of progressing to schizophrenia and guide early intervention.

Methods: Latent class analysis (LCA) of psychotic symptoms collected from 40 (n = 40) methamphetamine dependent individuals with a history of psychotic symptoms but no history of a primary psychotic disorder.

Results: Three typologies were identified. In one, persecutory delusions dominated (Type 1), in another persecutory delusions were accompanied by hallucinations (Type 2), and in the third a high frequency of all the assessed hallucinatory and delusional symptoms was observed (Type 3).

Discussion and conclusion: MAP is a heterogeneous syndrome with positive symptom typologies.

Scientific significance: This study represents the first attempt at identifying typologies of MAP and highlights the potential utility of LCA in future large-scale studies.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Declaration of Interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.

Figures

Figure 1
Figure 1
Estimated probabilities for the occurrence of 14 psychotic symptoms by latent class. AH, auditory hallucinations; MR, delusions of mind being read; REF, delusions of reference; VH, visual hallucinations
See this image and copyright information in PMC

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