Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Dec;30(4):462-478.
doi: 10.1111/maq.12215. Epub 2015 May 15.

Beyond Comorbidity: A Critical Perspective of Syndemic Depression and Diabetes in Cross-cultural Contexts

Affiliations

Beyond Comorbidity: A Critical Perspective of Syndemic Depression and Diabetes in Cross-cultural Contexts

Emily Mendenhall. Med Anthropol Q. 2016 Dec.

Abstract

This article examines the comorbidity concept in medical anthropology. I argue that the dearth of articles on comorbidity in medical anthropology may result from the rise of syndemic theory. Syndemics recognize how social realities shape individual illness experiences as well as distribution of diseases across populations. I discuss synergistic interactions foundational to the syndemics construct through my research of depression and diabetes comorbidity in vulnerable populations from urban United States, India, and South Africa. I argue that social and economic factors that cluster with depression and diabetes alone and together exemplify the biosocial processes that are at the heart of syndemics. In doing so, I illustrate how social, cultural, and economic factors shape individual-level experiences of co-occurring diseases despite similar population-level trends. Finally, I discuss the relevance of syndemics for the fields of medicine and public health while cautioning what must not be lost in translation across disciplines.

Keywords: Type 2 diabetes; comorbidity; depression; social inequality; syndemics.

PubMed Disclaimer

Figures

Figure 1
Figure 1
The VIDDA Syndemic. From Mendenhall (2012), Syndemic Suffering: Social Distress, Depression, and Diabetes among Mexican Immigrant Women. Reprinted with the permission of Left Coast Press, Inc., Walnut Creek, CA.

References

    1. Conant KL, Kaleeba JAR. Dangerous Liaisons: Molecular Basis for a Syndemic Relationship between Kaposi’s Sarcoma and P. Falciparum Malaria. Frontiers in Microbiology. 2013;4:1–14. - PMC - PubMed
    1. Coovadia H, Jewkes R, Barron P, Sanders D, McIntyre D. The Health and Health System of South Africa: Historical Roots of Current Public Health Challenges. Lancet. 2009;374:817–834. - PubMed
    1. Cowie CC, Rust KF, Byrd-Holt DD, Gregg EW, Ford ES, Guess LS, Bainbridge KE, Fradkin JE. Prevalence of Diabetes and High Risk for Diabetse Using A1C Criteria in the U.S. Population in 1988–2006. Diabetes Care. 2010;33:562–568. - PMC - PubMed
    1. Crowther NJ, Norris SA. The Current Waist Circumference Cut Point Used for the Diagnosis of Metabolic Syndrome in Sub-Saharan African Women Is Not Appropriate. PLoS ONE. 2012;7:e48883. - PMC - PubMed
    1. Deepa M, Anjana RM, Manjula D, Venkat Narayan KM, Mohan V. Convergence of Prevalence Rates of Diabetes and Cardiometabolic Risk Factors in Middle and Low Income Groups in Urban India: 10-year Follow-up of the Chennai Urban Population Study. Journal of Diabetes Science and Technology. 2011;5:918–927. - PMC - PubMed

Publication types

LinkOut - more resources