The polycystic ovary syndrome: an update on metabolic and hormonal mechanisms

Review

. 2015 Apr-Jun;8(2):142-5.

The polycystic ovary syndrome: an update on metabolic and hormonal mechanisms

R Dumitrescu¹, C Mehedintu², I Briceag³, V L Purcarea⁴, D Hudita⁴

Affiliations

¹ "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Gynecology Department, "Dr. I. Cantacuzino Hospital", Bucharest, Romania.
² "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Gynecology Department, "Nicolae Malaxa Hospital", Bucharest, Romania.
³ Gynecology Department, "Dr. I. Cantacuzino Hospital", Bucharest, Romania.
⁴ "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

PMID: 25866568
PMCID: PMC4392092

Review

The polycystic ovary syndrome: an update on metabolic and hormonal mechanisms

R Dumitrescu et al. J Med Life. 2015 Apr-Jun.

. 2015 Apr-Jun;8(2):142-5.

Authors

R Dumitrescu¹, C Mehedintu², I Briceag³, V L Purcarea⁴, D Hudita⁴

Affiliations

¹ "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Gynecology Department, "Dr. I. Cantacuzino Hospital", Bucharest, Romania.
² "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; Gynecology Department, "Nicolae Malaxa Hospital", Bucharest, Romania.
³ Gynecology Department, "Dr. I. Cantacuzino Hospital", Bucharest, Romania.
⁴ "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

PMID: 25866568
PMCID: PMC4392092

Abstract

Polycystic ovary syndrome (PCOs) is a public health important disease, affecting one in five women at reproductive age. The clinical implications include reproductive, metabolic and psychological features. This article reviews the literature data related to the new metabolic and hormonal mechanisms in PCOs. Recognizing the real diagnostic of PCOs, using the right criteria, is a challenge in current practice.

Keywords: PCOs; criteria; hyperandrogenism; infertility; insulin resistance.

PubMed Disclaimer

Cited by

Sexuality and psychological well-being in different polycystic ovary syndrome phenotypes compared with healthy controls: a cross-sectional study.
Bahadori F, Jahanian Sadatmahalleh S, Montazeri A, Nasiri M. Bahadori F, et al. BMC Womens Health. 2022 Sep 25;22(1):390. doi: 10.1186/s12905-022-01983-9. BMC Womens Health. 2022. PMID: 36155624 Free PMC article.
The effect of polycystic ovarian syndrome on fibrocystic breast changes in postmenopausal women.
Dang B, Clewis M, Miles B, Nguyen Q. Dang B, et al. Proc (Bayl Univ Med Cent). 2024 Feb 1;37(3):432-436. doi: 10.1080/08998280.2024.2308458. eCollection 2024. Proc (Bayl Univ Med Cent). 2024. PMID: 38628327 Free PMC article.
A comprehensive insight into effects of green tea extract in polycystic ovary syndrome: a systematic review.
Maleki V, Taheri E, Varshosaz P, Tabrizi FPF, Moludi J, Jafari-Vayghan H, Shadnoush M, Jabbari SHY, Seifoleslami M, Alizadeh M. Maleki V, et al. Reprod Biol Endocrinol. 2021 Sep 23;19(1):147. doi: 10.1186/s12958-021-00831-z. Reprod Biol Endocrinol. 2021. PMID: 34551795 Free PMC article.
The impact of vitamin D3 administration and of high fat diet on oxidative stress and inflammation in experimentally induced polycystic ovary syndrome.
Vulcan T, Suciu TS, Lenghel LM, Toma VA, Decea N, Moldovan R, Mitrea DR, Baldea I, Filip GA. Vulcan T, et al. Med Pharm Rep. 2024 Oct;97(4):516-527. doi: 10.15386/mpr-2798. Epub 2024 Oct 30. Med Pharm Rep. 2024. PMID: 39502756 Free PMC article.
Single nucleotide polymorphisms in the TGF-β1 gene are associated with polycystic ovary syndrome susceptibility and characteristics: a study in Korean women.
Roh EY, Yoon JH, Song EY, Kim JJ, Hwang KR, Seo SH, Shin S. Roh EY, et al. J Assist Reprod Genet. 2017 Jan;34(1):139-147. doi: 10.1007/s10815-016-0824-z. Epub 2016 Oct 29. J Assist Reprod Genet. 2017. PMID: 27796807 Free PMC article.

See all "Cited by" articles

References

1. Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab. 1998;83:3078–3082. - PubMed
1. Diamanti-Kandarakis E, Kouli CR, Bergiele AT, Filandra FA, Tsianateli TC, Spina GG, Zapanti ED, Bartzis MI. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. J Clin Endocrinol Metab. 1999;84:4006–4011. - PubMed
1. Carmina E, Lobo RA. Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women. J Clin Endocrinol Metab. 1999;84:1897–1899. - PubMed
1. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab. 2004;89:2745–2749. - PubMed
1. Asunción M, Calvo RM, San Millán JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab. 2000;85:2434–2438. - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

LinkOut - more resources

Full Text Sources
- Europe PubMed Central
- PubMed Central
Medical
- MedlinePlus Health Information

[1] Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab. 1998;83:3078–3082. - PubMed

[2] Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz R. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab. 1998;83:3078–3082. - PubMed

[3] Diamanti-Kandarakis E, Kouli CR, Bergiele AT, Filandra FA, Tsianateli TC, Spina GG, Zapanti ED, Bartzis MI. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. J Clin Endocrinol Metab. 1999;84:4006–4011. - PubMed

[4] Diamanti-Kandarakis E, Kouli CR, Bergiele AT, Filandra FA, Tsianateli TC, Spina GG, Zapanti ED, Bartzis MI. A survey of the polycystic ovary syndrome in the Greek island of Lesbos: hormonal and metabolic profile. J Clin Endocrinol Metab. 1999;84:4006–4011. - PubMed

[5] Carmina E, Lobo RA. Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women. J Clin Endocrinol Metab. 1999;84:1897–1899. - PubMed

[6] Carmina E, Lobo RA. Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women. J Clin Endocrinol Metab. 1999;84:1897–1899. - PubMed

[7] Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab. 2004;89:2745–2749. - PubMed

[8] Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab. 2004;89:2745–2749. - PubMed

[9] Asunción M, Calvo RM, San Millán JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab. 2000;85:2434–2438. - PubMed

[10] Asunción M, Calvo RM, San Millán JL, Sancho J, Avila S, Escobar-Morreale HF. A prospective study of the prevalence of the polycystic ovary syndrome in unselected Caucasian women from Spain. J Clin Endocrinol Metab. 2000;85:2434–2438. - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

The polycystic ovary syndrome: an update on metabolic and hormonal mechanisms

Affiliations

The polycystic ovary syndrome: an update on metabolic and hormonal mechanisms

Authors

Affiliations

Abstract

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Abstract

Similar articles

Cited by

References

Publication types

MeSH terms

Substances

Related information

LinkOut - more resources

Full Text Sources

Medical