Neuraxial dexmedetomidine: wonder drug or simply harmful
- PMID: 25866711
- PMCID: PMC4389101
- DOI: 10.5812/aapm.22651
Neuraxial dexmedetomidine: wonder drug or simply harmful
Keywords: Analgesia; Anesthesia; Dexmedetomidine.
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References
-
- Kalso EA, Poyhia R, Rosenberg PH. Spinal antinociception by dexmedetomidine, a highly selective alpha 2-adrenergic agonist. Pharmacol Toxicol. 1991;68(2):140–3. - PubMed
-
- Bloor BC, Ward DS, Belleville JP, Maze M. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology. 1992;77(6):1134–42. - PubMed
-
- Ebert TJ, Hall JE, Barney JA, Uhrich TD, Colinco MD. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology. 2000;93(2):382–94. - PubMed
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