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Case Reports
. 2017 Sep;27(5):910-913.
doi: 10.3109/14397595.2015.1038879. Epub 2015 May 28.

Henoch-Schönlein purpura nephritis occurring postpartum in a patient with anti-PL-7 anti-synthetase syndrome

Kojiro Nagai  1 , Jun Kishi  2 , Shun Morizumi  2 , Jun Minakuchi  3 , Yoshimi Bando  4 , Yasuhiko Nishioka  2 , Toshio Doi  1
Affiliations
Case Reports

Henoch-Schönlein purpura nephritis occurring postpartum in a patient with anti-PL-7 anti-synthetase syndrome

Kojiro Nagai et al. Mod Rheumatol. 2017 Sep.

Abstract

A 37-year-old pregnant woman developed purpura which was subsequently diagnosed as Henoch-Schönlein purpura (HSP). After childbirth, the patient developed proteinuria and hematuria. Further examination revealed that the HSP nephritis (HSPN) was associated with anti-threonyl-tRNA synthetase anti-synthetase syndrome. The onset of HSPN during pregnancy or after childbirth is rare. Moreover, to our knowledge, this is the first case to describe renal involvement in anti-synthetase syndrome.

Keywords: Anti-synthetase syndrome; Henoch–Schönlein purpura nephritis; Interstitial lung disease; PL-7; Pregnancy.

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