Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Apr 13:2015:bcr2014205237.
doi: 10.1136/bcr-2014-205237.

H1N1 pneumonitis associated with long-term non-steroidal anti-inflammatory drug abuse

Emma Prower  1 , Ozair Hasnain  2 , Chris Oscier  2
Affiliations
Case Reports

H1N1 pneumonitis associated with long-term non-steroidal anti-inflammatory drug abuse

Emma Prower et al. BMJ Case Rep. .

Abstract

This case series discusses two similar presentations of H1N1 influenza in young patients with a background history of long-term non-steroidal anti-inflammatory drug (NSAID) abuse. Both patients presented with type 1 respiratory failure requiring intensive care unit admission and subsequent organ support. This report reviews the immunosuppressive effects of long-term NSAID use and highlights a potential link to the significant morbidity seen.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Case 1 chest CT.
Figure 2
Figure 2
Case 2 CT pulmonary angiogram.
See this image and copyright information in PMC

References

    1. Health protection Agency. (Version 3 Jan 2011). Critical care management of adults with Influenza with particular reference to H1N1 2009.
    1. Jaber S, Conseil M, Coisel Y et al. . ARDS and influenza A (H1N1): patients characteristics and management in intensive care unit. A literature review. Ann Fr Anaesth Reanim 2010;29:117–25. 10.1016/j.annfar.2009.12.026 - DOI - PubMed
    1. Bautista E, Chotpitayasunondh T, Gao Z et al. , Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med 2010;362:1708–19. 10.1056/NEJMra1000449 - DOI - PubMed
    1. Inaoka M, Kimishima M, Takahashi R et al. . Non-steroidal anti-inflammatory drugs selectively inhibit cytokine production by NK cells and γδ T cells. Exp Dermatology 2006;15:981–90. 10.1111/j.1600-0625.2006.00505.x - DOI - PubMed
    1. Cianferoni A, Schroeder J, Kim J et al. . Selective inhibition of interleukin-4 gene expression in human T cells by aspirin. Blood 2001;97:1742–9. 10.1182/blood.V97.6.1742 - DOI - PubMed

Publication types

MeSH terms

Substances