Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Feb;27(1):27-30.
doi: 10.5455/msm.2014.27.27-30. Epub 2015 Feb 21.

Clinical and Epidemiological Characteristics of HIV Infection/AIDS in Hospitalized Patients

Sead Ahmetagic  1 , Humera Porobić-Jahic  1 , Dilista Piljic  1 , Amer Custovic  2 , Damir Sabitovic  3 , Denis Zepic  1
Affiliations

Clinical and Epidemiological Characteristics of HIV Infection/AIDS in Hospitalized Patients

Sead Ahmetagic et al. Mater Sociomed. 2015 Feb.

Abstract

Introduction: More than three decades after recognition of acquired immunodeficiency syndrome (AIDS) in the United States, the pandemic of human immunodeficiency virus (HIV) infection has dramatically changed the global burden of disease.

Aim: The main goal of this research is retrospective analysis of epidemiological and clinical characteristics of 28 HIV infected patients, who were diagnosed and treated at the Clinic for Infectious Diseases in University Clinical Center Tuzla in the period from 1996 until the end of 2013.

Subjects and methods: Retrospective analysis was performed using the medical records of 28 HIV-infected persons. Two rapid tests were used for HIV testing: OraQuick Advance test, Vikia HIV1/2, Elisa combo test, HIV RNA test. AIDS disease was determined by using the criteria from WHO.

Results: Among a total of 28 HIV-infected persons, 23 (82.14%) were males and 5 (17.86%) were females, with the male: female ratio of 4,6:1. In terms of the transmission route, a large proportion of cases were infected through heterosexual contact 19 (67.86%). At the time of the first visit, 16 (57.15%) patients showed asymptomatic HIV infection, 4 (14.28%) HIV infection with symptoms other than the AIDS defining diseases, and 8 (28.57) had AIDS. At the time of first hospital visit, the CD4 + cells count ranged from 40 to 1795/µl (conducted in 19 patients), and mean value of CD4 + cells was 365,31/µl, and mean HIV RNA titer was 287 118 copies/ml³. Of 28 HIV-infected persons 39 cases of opportunistic diseases developed in 12 patients (42.9%). In terms of the frequency of opportunistic diseases, tuberculosis (12 cases, 42.9%). Among a total of 28 HIV-infected patients, 6 (21.4%) of them died.

Conclusion: This study characterizes the epidemiological and clinical patterns of HIV-infected patients in Tuzla region of Bosnia and Herzegovina to accurately understand HIV infection/AIDS in our region, in the hope to contribute in the establishment of effective HIV guidelines in the Tuzla region of B&H in the future.

Keywords: HIV; clinical characteristics; epidemiology; hospitalized patients.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST: NONE DECLARED.

References

    1. Piot P, Carael M. Global Perspectives on Human Immunodeficiency Virus Infection and Acqired Immunodeficiency Syndrome. In: Mandel GL, Benet JE, Dolin R, editors. Principles and practice of Infectious Diseases. Philadelphia: Churchill Livingstone, Elsevier; 2010. pp. 1619–1633.
    1. Ezzati M, Lopez AD, Rodgers A, et al. Selected major risk factors and global and regional burden of disease. Lancet. 2002;360:1347–1360. - PubMed
    1. Geneve Switzerland: 2011. UNAIDS. GLOBAL HIV/AIDS RESPONSE. Epidemic update and health sector progress towards Universal Access Progress Report 2011.
    1. Geneve, Switzerland: 2014. UNAIDS. The Gap Report.
    1. Zavod za javno zdravstvo Federacije Bosne i Hercegovine. http://www.zzjzfbih.ba .

LinkOut - more resources