Thymus vulgaris essential oil: chemical composition and antimicrobial activity
- PMID: 25870697
- PMCID: PMC4391421
Thymus vulgaris essential oil: chemical composition and antimicrobial activity
Abstract
The study was designed to determine the chemical composition and antimicrobial properties of the essential oil of Thymus vulgaris cultivated in Romania. The essential oil was isolated in a yield of 1.25% by steam distillation from the aerial part of the plant and subsequently analyzed by GC-MS. The major components were p-cymene (8.41%), γ-terpinene (30.90%) and thymol (47.59%). Its antimicrobial activity was evaluated on 7 common food-related bacteria and fungus by using the disk diffusion method. The results demonstrate that the Thymus vulgaris essential oil tested possesses strong antimicrobial properties, and may in the future represent a new source of natural antiseptics with applications in the pharmaceutical and food industry.
Keywords: GC-MS analysis; antimicrobial activity; essential oil; thyme.
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References
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- Grigore A, Paraschiv I, Colceru-Mihul S, Bubueanu C, Draghici E, Ichim M. Chemical composition and antioxidant activity of Thymus vulgaris L. volatile oil obtained by two different methods. Romanian Biotechnological Letters. 2010;15(4):5436–5443.
-
- European pharmacopoeia. 5 ed. Strasbourg: Council of Europe: E.P.C.; 2004. pp. 217–218.
-
- Rota MC, Herrera A, Martínez RM, Sotomayor JA, Jordán MJ. Antimicrobial activity and chemical composition of Thymus vulgaris, Thymus zygis and Thymus hyemalis essential oils. Food Control. 2008;19(7):681–687.
-
- Thompson JD, Chalchat JC, Michet A, Linhart YB, Ehlers B. Qualitative and quantitative variation in monoterpene co-occurrence and composition in the essential oil of Thymus vulgaris chemotypes. Journal of Chemical Ecology. 2003;29(4):859–880. - PubMed
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