The need for treatment interruption studies and biomarker identification in the search for an HIV cure
- PMID: 25870989
- PMCID: PMC4529360
- DOI: 10.1097/QAD.0000000000000658
The need for treatment interruption studies and biomarker identification in the search for an HIV cure
Conflict of interest statement
J.Z.L. has served as a consultant for Quest Diagnostics, SeraCare Life Sciences and TherapyEdge. J.W.M is a consultant to Gilead Sciences and a shareholder of RFS Pharmaceuticals. D.M.S. has served as a consultant for Hologic and Testing Talent Services.
Comment in
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Can we avoid treatment interruption studies in the search for an HIV cure?AIDS. 2015 Jul 31;29(12):1575-7. doi: 10.1097/QAD.0000000000000763. AIDS. 2015. PMID: 26244397 No abstract available.
References
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- El-Sadr WM, Lundgren JD, Neaton JD, Gordin F, Abrams D, Arduino RC, et al. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med. 2006;355:2283–2296. - PubMed
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- Routy JP, Boulassel MR, Nicolette CA, Jacobson JM. Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy. J Med Virol. 2012;84:885–889. - PubMed
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- Schooley RT, Spritzler J, Wang H, Lederman MM, Havlir D, Kuritzkes DR, et al. AIDS clinical trials group 5197: a placebo-controlled trial of immunization of HIV-1-infected persons with a replication-deficient adenovirus type 5 vaccine expressing the HIV-1 core protein. J Infect Dis. 2010;202:705–716. - PMC - PubMed
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