[Non-celiac gluten sensitivity]
- PMID: 25873118
[Non-celiac gluten sensitivity]
Abstract
Non-celiac gluten sensitivity has recently been recognized by the scientific community as a part of gluten-related disorders, and is defined as a condition with gastrointestinal and/or extra-intestinal symptoms triggered by gluten ingestion in the absence of celiac disease and wheat allergy. Currently, there is no specific serological marker and non-celiac gluten sensitivity remains a diagnosis of exclusion: testing for celiac disease and wheat allergy must be negative, symptoms must improve with a gluten-free diet, and diagnosis must be confirmed by the gluten challenge. In this article, we discuss current knowledge of pathophysiology, clinical and epidemilogical spectrum, diagnosis, and treatment of NCGS.
Keywords: celiac disease - FODMAPs - gluten-free diet - gluten-related disorders - irritable bowel syndrome - non-celiac gluten sensitivity - wheat allergy..
Comment in
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[Non-celiac gluten sensitivity].Vnitr Lek. 2015 Mar;61(3):193-4. Vnitr Lek. 2015. PMID: 25873112 Czech. No abstract available.
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[Non-celiac gluten sensitivity].Vnitr Lek. 2015 Mar;61(3):195-6. Vnitr Lek. 2015. PMID: 25873113 Czech. No abstract available.
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