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. 2015 Apr 14;112(15):4509-11.
doi: 10.1073/pnas.1500963112.

News feature: Capturing cancer's complexity

Sarah C P Williams

News feature: Capturing cancer's complexity

Sarah C P Williams. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

None
The images reveal tumor heterogeneity by comparing distant metastases in the same patient, in the spleen (Left) and lung (Right). Images courtesy of Kornelia Polyak (Harvard Medical School, Boston) (10).
See this image and copyright information in PMC

References

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    1. Mroz EA, Rocco JW. MATH, a novel measure of intratumor genetic heterogeneity, is high in poor-outcome classes of head and neck squamous cell carcinoma. Oral Oncol. 2013;49(3):211–215. - PMC - PubMed
    1. Naxerova K, et al. Hypermutable DNA chronicles the evolution of human colon cancer. Proc Natl Acad Sci USA. 2014;111(18):E1889–E1898. - PMC - PubMed
    1. Marusyk A, et al. Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Nature. 2014;514(7520):54–58. - PMC - PubMed

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