Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015;18(1):53-60.
doi: 10.18433/j3k89d.

Hyaluronic acid and wound healing

Manuela G Neuman  1 , Radu M Nanau, Loida Oruña-Sanchez, Gabriel Coto
Affiliations
Free article

Hyaluronic acid and wound healing

Manuela G Neuman et al. J Pharm Pharm Sci. 2015.
Free article

Abstract

Background: We developed an experimental model of ethanol-induced dermatotoxicity and hepatocytoxicity using normal human keratinocytes and normal human hepatocytes that preserve inducible cytochrome p450 activities. The original work was described in several articles. The objective of this study was to determine whether hyaluronic acid attenuates skin necrosis, and to further clarify its uses in wound repair in humans, animal models and in vitro studies.

Methods: We performed a systematic review of the literature using the terms "hyaluronic acid" and "wound healing". PubMed was searched for studies published during the period 2010-2014.

Results: Hyaluronic acid is used in tissue regeneration alone or in combination with herbal or Western medicine. Scaffolds made up of hyaluronic acid were used to embed basic fibroblast growth factor.

Conclusion: Hyaluronic acid extracts are safe and efficacious products to be used in skin repair.

PubMed Disclaimer

Publication types

LinkOut - more resources